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deeming these products to be subject policy within the rapidly evolving to FDA regulation,31 may depend tobacco product patterns of use, ABBREVIATIONS on the availability of resources new national regulation,and poorly ALA: American Lung Association for universal annual compliance regulated Internet sales. Cl: confidence interval checks and enforcement targeted e-cigarette: electronic cigarette to both traditional and alternative ACKNOWLEDGMENT FDA: US Food and Drug tobacco product vendors.Continued April Roeseler provided useful Administration OR: odds ratio monitoring is needed to assess the comments on the development of the TRL: tobacco retail licensing impact on the effectiveness of TRL article. FINANCIAL DISCLOSURE:The authors have indicated they have no financial relationships relevant to this article to disclose. FUNDING:Supported by grant P50CA180905 from the National Cancer Institute at the National Institutes of Health(NIH)and the US Food and Drug Administration Center for Tobacco Products and by grant 1 R21 HD084812-01 from the Eunice Kennedy Shriver National Institute for Child Health and Human Development at the NIH.No funders had any role in the design and conduct ofthe study;collection,management,analysis,or interpretation ofthe data;or preparation,review,or approval of the manuscript.The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH or the US Food and Drug Administration.Funded by the National Institutes of Health(NIH). POTENTIAL CONFLICT OF INTEREST:The authors have indicated they have no potential conflicts of interest to disclose. REFERENCES 1. Centers for Disease Control (CDC). can be expected to reduce smoking? 12. 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