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deeming these products to be subject policy within the rapidly evolving <br />to FDA regulation,31 <br />may depend tobacco product patterns of use, <br />ABBREVIATIONS <br />on the availability of resources new national regulation,and poorly ALA: American Lung Association <br />for universal annual compliance regulated Internet sales. Cl: confidence interval <br />checks and enforcement targeted e-cigarette: electronic cigarette <br />to both traditional and alternative ACKNOWLEDGMENT FDA: US Food and Drug <br />tobacco product vendors.Continued April Roeseler provided useful <br />Administration <br />OR: odds ratio <br />monitoring is needed to assess the comments on the development of the <br />TRL: tobacco retail licensing <br />impact on the effectiveness of TRL article. <br />FINANCIAL DISCLOSURE:The authors have indicated they have no financial relationships relevant to this article to disclose. <br />FUNDING:Supported by grant P50CA180905 from the National Cancer Institute at the National Institutes of Health(NIH)and the US Food and Drug Administration <br />Center for Tobacco Products and by grant 1 R21 HD084812-01 from the Eunice Kennedy Shriver National Institute for Child Health and Human Development at the <br />NIH.No funders had any role in the design and conduct ofthe study;collection,management,analysis,or interpretation ofthe data;or preparation,review,or <br />approval of the manuscript.The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH or the US Food <br />and Drug Administration.Funded by the National Institutes of Health(NIH). <br />POTENTIAL CONFLICT OF INTEREST:The authors have indicated they have no potential conflicts of interest to disclose. <br />REFERENCES <br />1. 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